Case studies

Atlas Genetics io Reader: saving lives with point of care diagnostics

With infectious diseases, rapid diagnosis has the power to improve treatment compliance by eliminating the need for a follow-up visit and can, in some cases, be critical to survival. So, creating a world-class instrument that could deliver results in less than half an hour and at the point of care was ambitious but vital.

  • Client
    Atlas Genetics
Atlas Hero

Context

Rapid infectious disease diagnosis at the point of care enables the provision of earlier, more accurate and more effective treatment to patients, all of which limit the spread of infectious disease.

Solution

Working with Atlas Genetics, TTP created the Atlas io Reader®, a world-class diagnostic instrument for nucleic acid-based infectious disease testing at the point of care.

Result

The io Reader® provides Atlas Genetics with a competitive diagnostic platform that offers low cost, high accuracy and a sample-answer time of 30 mins.

TTP and Atlas Genetics created a point-of-care instrument for the diagnosis of infectious disease.

W

Working with Atlas Genetics, we developed the io Reader® which operates a test-specific cartridge that fully automates a three-stage process of DNA extraction and purification, amplification, and electrochemical detection - traditionally a complex laboratory process.

The operator simply adds a sample to the cartridge, inserts it into the reader, and follows the on-screen instructions.

We achieved a small instrument footprint, important to many laboratories, by using an effective, pneumatic, economic and mechanical architecture.

Quote

We chose TTP on the basis of ‘lowest risk/highest reward’. In particular I was impressed with the combination of TTP’s technical capabilities, structured approach and project management skills. The project was a great success because it had the right amount of innovation and practical engineering solutions; and all of the software development work went through the production and verification steps smoothly and on time (notable because project overruns frequently occur due to software failures). The first production units were delivered within the tight 12-month timeframe required at the end of 2013. This ensured that Atlas was on track with the time-table it had promised.

John Clarkson

Chief Executive, Atlas Genetics
Atlas Testing

Development Highlights

  • Achieving multiple interfaces (force, pneumatic, thermal, electronic) between instrument and cartridge.
  • Effecting a short, accurate and repeatable PCR temperature cycle.
  • Realising form factor acceptable to healthcare professionals.
  • Hitting tough cost targets.

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Hovione

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