Case studies

Refining the consistency of advanced drug delivery to the eye

  • Client
    Gyroscope Therapeutics Limited
Gyroscope Hero


Gyroscope wanted to refine the fluidic control elements of its innovative Orbit™ Subretinal Delivery System (Orbit SDS™) medical device, which enables precise microinjection into the subretinal space of the eye.


TTP’s experience of microfluidics, tolerance analysis, micro-prototyping and manufacturing came together to demonstrate enhanced fluidic and dosing performance with prototyped parts within the tight space constraints of Gyroscope’s device.


TTP’s expertise and recommendations allowed Gyroscope to commit to creating moulded components and transfer to manufacture for the new concept.


Gyroscope (now a Novartis Company) has developed world-leading products for delivery to the subretinal space of the eye without the need for a vitrectomy or retinotomy.

Gyroscope wanted to refine the fluidic control elements of its innovative Orbit SDS™ medical device and approached TTP to identify potential ways to achieve this.

Gyroscope Intext

TTP reviewed the fluid control functionality of the device and generated alternative solutions for fluid control and sealing. Using an analytical approach, we were able to recommend a preferred solution from a number of concepts and to define the required tolerances to meet Gyroscope’s performance requirements. The use of an analytical approach also minimised the need for design iterations and enabled us to quickly create proof-of-concept test pieces for Gyroscope.

TTP then used a combination of rapidly prototyped parts and machined components to simulate final moulded parts that incorporated our understanding of manufacturing processes, tolerances and materials to provide compatibility with existing components of Gyroscope’s device.

These sample devices supported more detailed testing at TTP and Gyroscope, including accelerated aging and of overall fluidic and dosing performance using a test protocol and an absorbance assay developed by TTP. 


When we received the new moulded parts incorporating TTP’s recommendations, all of them performed as intended and within specification. We were really excited.

Justin Creel

Vice President of Device Development, Gyroscope Therapeutics Limited

By combining analytical design approaches with deep knowledge of medical devices and manufacturing techniques, Gyroscope was able to create moulded components to improve their ground-breaking medical device. 

Get in touch

Next up

Ultrasonic Cleaning Demo

  • Industries
    Industrial Products, Industrial Safety, Autonomous Driving
Ultrasonic Sensing

We use cookies to improve your experience on our site. To find out more, read our updated privacy policy. More information.