Drug delivery device development
Design and engineering experts in advanced drug delivery systems
TTP is trusted by nine of the top ten global pharmaceutical leaders to solve complex drug delivery challenges. As a design and engineering consultancy specialising in advanced drug delivery devices and combination products, we help teams take devices from blank sheet to clinical reality, addressing challenges such as high-viscosity biologics and advanced formulations. With deep engineering, scientific and human factors expertise, our team guides you from early feasibility and concept creation through to design, verification, transfer to manufacture and launch. We focus on developing robust, efficient and scalable devices that support therapeutic effectiveness and perform reliably in real-world use.
Expertise in complex drug delivery systems and combination products
Bringing life-changing drug delivery systems and combination products to market is inherently complex. Device teams face challenges around viscosity, manufacturability, usability and regulatory requirements - any of which can delay launch.
TTP’s drug delivery specialists help pharmaceutical and biotech organisations accelerate development, retire risks early and balance the trade-offs required to create robust, commercially successful devices. We have contributed to more than 70 innovative systems, including autoinjectors, inhalation devices, microneedles, infusion pumps and advanced local-delivery systems.
Our core drug delivery expertise includes:
- Parenteral device development for biologics, complex formulations and high-viscosity drugs, including autoinjectors, pens and wearable injectors
- Respiratory drug delivery, including pMDIs, DPIs and nebulisers
- Local and targeted delivery systems, implantables and sustained-release technologies
- Advanced device engineering, human factors insight, modelling, verification, and design for manufacturability
We work in agile, multidisciplinary teams that can adapt rapidly to project needs, resolve technical challenges early and prevent costly downstream issues. Using first-principles engineering, scientific rigour and probabilistic methods, we identify variability in materials, processes and user interaction to set specifications that ensure consistent device performance throughout the lifecycle.
This approach is why global pharma and biotech companies bring us their most critical, high-impact programmes, and why our work has enabled launches such as AstraZeneca’s Symbicort® dose counter.
Need support with a complex device or formulation challenge?
TTP have been an invaluable long-term partner for AstraZeneca. They have both the deep expertise and creativity to generate innovative concepts, and the horsepower to accelerate these through design verification.
Dan Deaton
Executive Director, Patient Experience & Innovation at AstraZeneca
TTP has been an incredible partner, complementing our expertise and delivering designs from white board to moulded functional prototypes. With TTP’s support, Achilles is scaling our manufacturing process and bringing transformative therapies from bench to bedside. The TTP team has shown the same level of excitement as us in getting these therapies to the people who need them.
Ed Samuel
EVP Technical Operations
When we received the new moulded parts incorporating TTP’s recommendations, all of them performed as intended and within specification. We were really excited.
Justin Creel
Vice President of Device Development
Parenteral device innovation: autoinjectors, pens and wearables
TTP' has a proven track record in the drug delivery product development process, particularly parenteral device innovation, playing a key role in more than eight mechanical injection devices now on the market, with many more in the pipeline.
Our consultants have supported clients on a range of drug delivery technologies - from variable dose pens and autoinjectors to ophthalmic injectors and wearable devices.
Our current work is helping address many of the challenges that the industry is currently facing, such as:
- Developing devices for complex and challenging formulations
We engineer injection devices that reliably handle high-viscosity biologics, particulate suspensions and primary-pack interactions to prevent issues like clogging and delivery failures.
- Engineering reliable, scalable autoinjectors and pens
We resolve performance and reliability issues in autoinjectors, pens and wearables during scale-up by optimising device mechanics, tolerances and assembly processes. Read more.
- Designing sustainable next-generation injection devices
We create ISO 11608–aligned parenteral systems that integrate reusable elements, recyclable materials and separability to meet sustainability goals without compromising performance or usability.
Explore how TTP is advancing next-generation drug delivery solutions for advanced therapies, addressing challenges in high-viscosity mAbs and particulate suspensions through expertise in fluid dynamics, material science, and patient-focused design.
Accelerating respiratory drug delivery device development - pMDIs, DPIs, and nebulisers
Respiratory drug delivery requires alignment of formulation, aerosol science, device design and manufacturability to ensure consistent and effective dosing, patient ease-of-use, and scalable production. Each component influences the other - formulation impacts aerosol performance, which shapes device design, and manufacturability determines production feasibility. TTP’s expertise minimises risks, mitigates delays, and accelerates time to market by enabling optimisation across all areas.
We’ve developed more than 35 respiratory devices ranging from simple to advanced systems - including pMDIs, DPIs, soft mist inhalers, mesh nebulisers and other delivery devices - many of which are now market-leading products.
With deep scientific understanding and cross-industry insight, we drive innovation in both next-generation devices and generics - even in crowded IP landscapes.
As respiratory drug delivery advances, we lead the way in developing technologies essential for future therapies like biologics, mRNA and other future therapies.
Discover how TTP’s TouchSpray™ atomiser technology revolutionised respiratory drug delivery, powering the PARI eFlow® nebuliser to cut treatment time by 50% while delivering 90% drug efficacy and unmatched portability for patients worldwide.
Local and targeted drug delivery systems and implantable devices
Targeted drug delivery promises to revolutionise treatment efficacy by concentrating therapeutics at the site of action while minimising systemic exposure. From oncology to neurology, ophthalmology to pulmonary delivery, these therapies demand delivery systems that are not only scientifically robust but finely tuned to the anatomical, physiological and pathological nuances of the target site.
At TTP, we’re helping our partners navigate the complexity of local and targeted delivery. Our multidisciplinary teams combine deep understanding of tissue biology, pharmacokinetics and advanced materials with engineering excellence to design devices and procedures that deliver with pinpoint accuracy and inspire clinician confidence in a surgical environment.
We have expertise in a wide range of delivery modalities, including:
- Intraocular and intravitreal injectors designed for sustained or repeated dosing
- Intratumoural delivery systems optimised for localised chemotherapy or immunotherapy
- Implantable and biodegradable devices enabling sustained release at the target site
Our solutions are underpinned by first-principles thinking and modelling of tissue interactions, device mechanics, and human factors - ensuring performance from bench to bedside. With patient comfort, clinical usability, and manufacturing feasibility built in from the start, we help you unlock the potential of localised drug delivery to achieve better therapeutic outcomes, faster.
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How we can help
Accelerating inhaled drug delivery innovation
TTP integrates expertise in aerosol science, formulation, device design and manufacturing to optimise performance, ensure patient ease-of-usemand accelerate time to market. With a proven track record across pMDIs, DPIs, nebulisers, and inhalers, we drive next-generation respiratory therapies, from biologics to mRNA delivery.
Advancing drug delivery for complex formulations
TTP specialises in developing innovative drug delivery solutions for advanced formulations, including cell and gene therapies, viral vectors and other advanced treatments. Our expertise in formulation stability, precision dosing, and device design ensures scalable, patient-centric solutions that accelerate development while meeting stringent regulatory requirements.
Engineering the future of parenteral drug delivery
From wearable injectors to autoinjectors and ophthalmic delivery, TTP applies deep engineering and scientific expertise to optimise injectable drug delivery. We tackle challenges such as high-viscosity biologics, device reliability at scale and sustainability, helping pharmaceutical companies accelerate innovation while ensuring performance and patient safety.
Regulatory expertise in medical device development
We help ensure your device development aligns with the relevant standards, preparing the robust design history files required for regulatory submission. Our ISO 13485-certified quality system and deep technical expertise streamline development and reduce friction in later stages.
End-to-end drug delivery device design and development
From opportunity discovery and concept ideation to prototyping, regulated design development, and final transfer to manufacture, TTP provides comprehensive support at every stage of the product development cycle, ensuring a streamlined process that accelerates time-to-market and meets regulatory standards.
Accelerating inhaled drug delivery innovation
TTP integrates expertise in aerosol science, formulation, device design and manufacturing to optimise performance, ensure patient ease-of-usemand accelerate time to market. With a proven track record across pMDIs, DPIs, nebulisers, and inhalers, we drive next-generation respiratory therapies, from biologics to mRNA delivery.
Advancing drug delivery for complex formulations
TTP specialises in developing innovative drug delivery solutions for advanced formulations, including cell and gene therapies, viral vectors and other advanced treatments. Our expertise in formulation stability, precision dosing, and device design ensures scalable, patient-centric solutions that accelerate development while meeting stringent regulatory requirements.
Engineering the future of parenteral drug delivery
From wearable injectors to autoinjectors and ophthalmic delivery, TTP applies deep engineering and scientific expertise to optimise injectable drug delivery. We tackle challenges such as high-viscosity biologics, device reliability at scale and sustainability, helping pharmaceutical companies accelerate innovation while ensuring performance and patient safety.
Regulatory expertise in medical device development
We help ensure your device development aligns with the relevant standards, preparing the robust design history files required for regulatory submission. Our ISO 13485-certified quality system and deep technical expertise streamline development and reduce friction in later stages.
End-to-end drug delivery device design and development
From opportunity discovery and concept ideation to prototyping, regulated design development, and final transfer to manufacture, TTP provides comprehensive support at every stage of the product development cycle, ensuring a streamlined process that accelerates time-to-market and meets regulatory standards.
Our approach and capabilities
We deliver across the entire life of a project, from opportunity discovery to production engineering. Discover how our interdisciplinary teams of experts collaborate to tackle the toughest product development challenges.
Our campus and facilities
Our award-winning campus has been designed with a clear vision. To create a space which can support our people and our clients as we develop and deliver the very best technology solutions.
Software capability at TTP
Engaged in all stages of software and product development, our software capability at TTP covers the full spectrum—from in-depth analysis and system architecture to prototype design, implementation, and test development.
Manufacturing capability at TTP
Working seamlessly with our development teams, we take clients' products through prototype builds, clinical trials, pilot manufacture and more. Using TTP Manufacturing reduces uncertainty, risk and time to market for our clients.
Meet some of the team
Steve Gowers
Dan Lock
Harry Bullivant
Talk to us about your next project
We help clients with all stages of their most complex and challenging technology and product development projects.
If you're considering the next steps along your innovation journey, why not get in touch?